T cells

In a new study, researchers have found cellular mechanisms responsible for eliminating T cells that pose autoimmune dangers. Scientists at the Georgia Institute of Technology reported that in the newly discovered mechanisms, aggressively developing thymocytes are made to commit suicide to prevent them from causing damage to the body, while maintaining the normally developing thymocytes that grow into T cells and act against infections as well as cancer. Although the

RNA Sequencing

In a recent study, researchers have discovered a new method that use brain networks and supervised machine-learning techniques to efficiently identify cell types following single-cell RNA sequencing (scRNA-seq). Instead of depending on marker genes that are not available for all cell types, scientists at Carnegie Mellon University adopted the new automated technique to evaluate all scRNA-seq data and select just specific parameters required for differentiating one cell from another. The

3D Human Heart Tissue

Animal heart tissue will not be needed anymore for human drug testing, as researchers at the University Medical Center Hamburg-Eppendorf have discovered a technique to develop a 3D human heart tissue model that represents a beating human heart tissue. This is the first ever 3D human heart tissue model that emulates the exact function of the heart’s atria, which are the uppermost chambers of the heart, and it is grown

Human Thoughts

Scientists at Max Planck Institute for Human Cognitive and Brain Science have offered a conclusive answer to the most important question in neuroscience, ‘How do Humans Think?’ In the new proposal, featured in the journal Science, scientists explained that human thoughts use navigation system of the brain to think. Place cells and grid cells, situated in the hippocampus and neighboring entorhinal cortex of the brain respectively, are two important cell

Ecological Thinking and Sample Diversity can improve Psychological Science: Researchers

In a new paper, featured in the Proceedings of the National Academy of Sciences, researchers argued with the long-known cluster of five personality traits or ‘Big Five’ that universally determine the structure of human personality. For long, consensus among psychologists across the globe has held that five universal traits including conscientiousness, extraversion, openness, agreeableness and neuroticism, or a slight variation define human personality. However, in the recent study, a research

New Fluorescent Marker to Help Surgeons Identify and Remove Brain Tumor Cells Accurately

Fluorescent marker can enhance the rate of survival from one of the deadliest forms of brain tumors. In a trial presented at the 2018 NCRI Cancer Conference, scientists used a ‘fluorescent’ chemical that could highlight cancerous cells and help them identify and remove the most aggressive type of disease. The research involved 99 people who had suspected ‘glioma’. It is one of the most common forms of brain cancer that

Genetic Barcoding

Scientist from Icahn School of Medicine have been able to simultaneously evaluate the functions of hundreds of genes with resolution reaching single-cell level using a newly developed novel Genetic Barcoding technology. The study, featured in the recent issue of journal Cell, describes the new technology that relies on barcoding approach using a specific protein. Although the sequencing of human genome was pioneered by scientists in the early 2000s, revealing a

Digital Brain

Researchers at Steven Institute of Technology have created a 3D digital brain model to demonstrate the transportation of toxic proteins involved in neurodegenerative diseases to the brain. The model simulates the significant patterns of atrophy associated with Parkinson’s disease and Alzheimer’s diseases, by altering the starting point of toxic proteins in the brain. Researchers believe that this model will expand the understanding of such diseases. The study, set to be

Synthetic DNA Vaccine

Through the development of experimental vaccine platforms, many breakthroughs in Ebola virus disease (EVD) vaccine development have been achieved, including one recently developed Synthetic DNA Vaccine by researchers at The Wistar Institute Vaccine and Immunotherapy Center. According to the World Health Organization (WHO), Ebola triggers a severe hemorrhagic fever that kills nearly 50% of the population. Although few promising candidates of vaccine have been developed, they may be associated with

Vaccine Manufacturing

A team of researchers from the University of Texas Medical Branch at Galveston has recently developed a comparatively less expensive method for the Vaccine Manufacturing. Making use of this technique will help in cutting down the cost of the vaccine manufacturing production and the storage by around 80%. This cost-reduction can be done by reducing the effectiveness and safety of the vaccines. The research findings that have been conducted by